ea0081oc5.4 | Oral Communications 5: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2022
Dobbie Laurence J
, Zhao Sizheng Steven
, Pittam Bradley
, Alam Uazman
, Barber Thomas M
, Cuthbertson Daniel J
Background: Observational and genetic Mendelian randomisation (MR) data has demonstrated the association of adulthood overweight/obesity with development of polycystic ovary syndrome (PCOS). However, the contribution of early life (i.e. childhood/adolescence) body composition on incident PCOS is unclear. This study determines the influence of body composition on the likelihood of developing PCOS.Methods: We conducted a 2-sample Mendelian randomisation st...